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Therefore, the development of ALDH-responsive aPSs, capable of ROS generation and fluorescence monitoring in the CSC-enriched microenvironment, holds significant potential for the precise and high-efficiency treatment of CSC-enriched tumors
MMP, Matrix metalloproteinase
Affinity purification performed by gravity using TALON resin (Clontech), anion exchange performed using HiTrapQ FF (GE Healthcare), size-exclusion chromatography performed using Superdex 200 10/30 prep grade (GE Healcare) the later two performed using KTA FPLC platform
