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and low-risk patients (D/R) do not receive prophylaxis (5, 6)

In addition, vitamin B12 methylcobalamin injections raise the available amount of SAMe (S-adenosylmethionine), an important compound which lifts the mood and works as a tricyclic antidepressant

(PubMed) Fernandez-Roig S, Lai SC, Murphy MM, Fernandez-Ballart J, Quadros EV

The neurological consequences of untreated B12 deficiency can be serious and potentially permanent, including subacute combined degeneration of the spinal cord, which affects both sensory and motor pathways
