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Adenosylcobalamin is needed as cofactor in methylmalonyl-CoA mutaseMUT enzyme

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Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist approved by the FDA for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity

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However, Minot, Murphy, and Whipple received the joint Nobel Prize for discovering a cure for a previously fatal disease of unknown cause in 1934, becoming the first Americans to be awarded the Nobel Prize in Physiology and Medicine

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Symptoms can range from mild to severe

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