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Of the adverse experiences judged to be of "possible" relationship to the study drug, anxiety, incoordination, and nervousness were reported following intramuscular vitamin B12 and headache, nausea, and rhinitis were reported following dosing with Nascobal (Cyanocobalamin, USP) Gel for Intranasal Administration

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Metformin : This medication, used to treat diabetes, has been shown to reduce the absorption of vitamin B12 in the body and lower serum vitamin B12 concentrations in the blood

The difference between what patients experience at Perfect B and what they report from self-administration online is not the peptide itself