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The dimer interface is formed by the interaction between loop 2 of one monomer and loop 1 of the other, stabilized by hydrogen bonds and salt bridges, resulting in a more open and flexible active site pocket compared to other GCTs

Breach in intestinal permeability is mediated by the microbiota To further examine the link between the arthritis-related immune response, changed microbiota and intestinal epithelial barrier dysfunction, we applied different immunization protocols including (i) arthritogenic collagen type II + complete Freunds adjuvans (CII + CFA), (ii) denaturized CII + CFA (deCII + CFA) and (iii) CII without CFA (CII)

Signal transduction by mitochondrial oxidants

M., Martnez-Ramrez M