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We dont exclude the possibility of a similar adaptation taking place behind the scenes, bringing out worse symptoms for a temporary period
The 1 mg arm of Phase 2 produced direct measurement
doi:10.1016/0192-0561(88)90148-8 30
Clinical trials comparing oliceridine with morphine for pain following a bunionectomy (APOLLO-1) (Viscusi et al., 2019) or an abdominoplasty (APOLLO-2) (Singla et al., 2019) demonstrated a noninferior analgesic response and a more favorable gastrointestinal and respiratory tolerability profile with oliceridine
