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Description
190 Piceatannol (PIC), another natural arginase inhibitor, can effectively inhibit TGF-1 /TGF- receptor type 1 (TGF-R1) signaling pathway, limit M2-type macrophage polarization to regulate TME and inhibit CRC progression and metastasis

Di Bisceglie AM, Axiotis CA, Hoofnagle JH, Bacon BR

Serious adverse effects are very rare in published literature

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