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J Neurol 270:477485 Phokaewvarangkul O et al (2023) Homocysteine, vitamin B metabolites, dopamine-substituting compounds, and symptomatology in Parkinsons disease: clinical and therapeutic considerations

Patients with long-standing alcohol use, restrictive diets, malabsorption syndromes, or prolonged use of medications that deplete or interfere with B vitamins may particularly benefit when a deficiency is confirmed

The population for the analysis of the primary efficacy endpoint included, 36,621 participants 12 years of age and older (18,242 in the Pfizer-BioNTech COVID-19 Vaccine group and 18,379 in the placebo group) who did not have evidence of prior infection with SARS-CoV-2 through 7 days after the second dose