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Treatment of metformin-induced vitamin B12 deficiency As we stated before, several studies including interventional studies, observational studies, and meta-analyses concluded that chronic use of metformin could be a cause of vitamin B12 deficiency, and many complications may accompany this

The codes clinical utility extends beyond billing-it directs appropriate treatment toward parenteral B12 replacement rather than ineffective oral supplementation

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Any disagreements in the study selection process were resolved by a third person (Dang)