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Here are some signs of potential alcohol poisoning to watch for: Hypothermia (low body temperature), discolored skin color, paleness Mental confusion, stupor, coma, or person cannot be roused Irregular breathing (10 seconds or more between breaths) Slow breathing (fewer than eight breaths per minute) Vomiting Seizure In case of emergency, call GTPD: (404) 894-2500 Strategies for Cutting Down on Drinking Small changes can make a big difference in reducing your chances of having alcohol-related problems

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The widespread immune response and the random appearance of demyelinating lesions make it difficult to disentangle the intrinsic immune relevance of the CNS to disease progression and remyelination (Lassmann and Bradl, 2017