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People who are pregnant or breastfeeding, those with kidney disease, seizure disorders, or thyroid conditions, and anyone on medications that could interact should avoid it unless a physician specifically approves it

Stereological and histological studies exhibited that, after busulfan treatment, some large vacuoles were observed in the semi-niferous tubules in the rat testis and the size of seminiferous tubules was reduced, which was linked to disorganization and reduction of height of germinal epithelium following depletion of spermatogenic lineage cells (spermatogonia, spermatocytes, and round elongated spermatid)

In one study, untreated celiac patients were found to have low serum L-carnitine concentrations, which returned to normal with a gluten-free diet (Lerner 1993)

Tyni T, Pihko H, Kivela T
