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Jeon S, Carr R (2020) Alcohol effects on hepatic lipid metabolism

The mass lists obtained from each PMF analyzed, after exclusion of the contaminant mass values (autolytic tryptic peptides and tryptic human keratin fragments) by the PeakErazor program ( were used to search for protein candidates in (human) NCBLnr database consulting the Mascot search engine ( All searches respected the following parameters: one missed cleavage, 50 ppm measurement tolerance, oxidation at methionine (as variable modification)

Activated protein phosphatase-1 rapidly dephosphorylates and deactivates HSL, causing a fall in the rate of lipolysis (73, 92, 100, 119, 143)

It is important to note that neurological damage can occur before haematological changes become apparent, and symptom severity does not always correlate with the degree of biochemical deficiency