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glutathione acetaminophen detoxification Downregulation of Glutathione-Mediated Capacity by Binge Drinking Aggravates Acetaminophen-Induced Liver Injury through IRE1α ER Stress Signaling Early life acetaminophen exposure, glutathione
Description
Adverse effects observed in clinical trials include: Gastrointestinal effects: nausea, vomiting, diarrhoea, and constipation particularly during dose escalation

L., Luo, G

with [ X ] = drug concentration

cGAS-STING senses cytosolic double-stranded DNA and triggers an innate immune response through type I interferons