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Prenatal nutritional deficiency and risk of adult schizophrenia

It is evident that 5AMP and 5GMP manifest substantial circadian rhythms during the dark period (at 20:19 and 05:08, respectively), while 5CMP and 5IMP demonstrate notable circadian rhythms during the day (at 18:40 and 19:14, respectively)

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SIRT1 also indirectly modulates key molecules in the insulin signaling pathway, such as insulin receptor substrate 2 (IRS2) by influencing members of the forkhead transcription factors (FOXO) family, ultimately alleviating insulin resistance [108,109,110]
