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These findings are of interest to clinicians as melatonin protects against mitochondrial dysfunction, apoptosis, and dopaminergic degeneration, which are considered to contribute to several psychosomatic manifestations in METH abusers

Esposito C, Ugo Garzarella E, Santarcangelo C, Di Minno A, Dacrema M, Sacchi R, Piccinocchi G, Piccinocchi R, Daglia M (2021) Safety and efficacy of alpha-lipoic acid oral supplementation in the reduction of pain with unknown etiology: A monocentric, randomized, double-blind, placebo-controlled clinical trial