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Hoshyar N, Gray S, Han H, et al
C.InoueY.JohkohT.et al (2022a)
Similarly, in tauopathy-frontotemporal dementia models, both compounds showed neuroprotective effects, reversing memory impairments and reducing hippocampal atrophy
however, a thorough investigation of metabolites, therapeutic efficacy, pharmacodynamics, and tissue distribution will be required for safety before clinical validation through human trials can be performed
