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Description
The medial collateral ligament transection model showed BPC-157 treatment produced repairs capable of withstanding mechanical stress comparable to healthy ligaments

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AFM can measure the stiffness and viscoelastic properties of individual collagen fibrils and other ECM components, providing detailed information about how molecular structure relates to mechanical function

The mechanisms involve IGF-1-driven activation of the PI3K-Akt pathway in fibroblasts and epithelial cells, promoting both proliferation and survival during the repair process