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In another study, pre-treatment with 10 M curcumin showed positive effects in controlling microglia activity by deactivating NFB and AP-1 pathways and inhibiting the gene expressions of pro-inflammatory factors such as TNF, iNOS, COX-2, PGE 2 and IL-1 [292]

The dorsal central region of the rat retina is considered a functional analogue of the human macular, which is the sharpest visual area ( The animal model of blue light damage is generally selected from 56 week old SD rats, which need to undergo 7 days of adaptive feeding and dark maintenance before officially starting modeling

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The discussion of MASLD and WD further elucidated the intricate link between copper, cuproptosis, and lipid metabolism