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We believe that Dihexa can serve as an excellent candidate molecule to augment limb function following peripheral nerve damage
The environment of Phe1035 can also be stabilised by nearby Arg446(Arg118) involved in the dmIR-ECD/hIR conserved hydrogen bonds triad with Tyr419(Tyr91) and Glu448(Glu120), with a potential Arg446 guanidinium--Phe1035(Phe705) interaction as well
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1998;275(1):R2129
