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Human growth hormone, or HGH, is released by the pituitary gland to promote height in puberty, muscle growth, and bone strength (3)

In neuronal cells, following the knockdown of PINK1 and Parkin, PINK1 is observed to promote PARIS ubiquitination and Parkin proteasomal degradation through phosphorylation of Parkin and PARIS

However, these uncontrolled observations require validation through prospective, controlled clinical trials before establishing standard treatment durations for specific clinical indications