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4d, statistically significantly different from LD controls and vehicle-treated mice switched from WD to LD)

[6] [3] [10] A mild deficiency may not cause any discernible symptoms, but moderate deficiency can cause various symptoms, such as feeling tired, lightheadedness, headaches, cold intolerance, pale skin, sore tongue, upset stomach, loss of appetite, hair and skin color changes, numbness or tingling (pins and needles) of the fingers and toes, and tinnitus, and vision, cognitive or psychological problems

Cyanocobalamin, by contrast, requires enzymatic conversion in the liver and tissues to become active

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