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Challenges and Future Directions 8.1

Curcumin blocks NF-kB activation, resulting in lower levels of TNF- and thrombotic plasminogen activator inhibitor type 1 (238)

NADH and lactate accumulate, and all the components of the mitochondrial electron transport system are saturated with electrons (reduced), because the electrons cannot be transferred to oxygen

Major trauma, including heat injury to the skin, results in a profound loss of body nitrogen, altered rates of whole-body protein synthesis and breakdown, and increased nitrogen and amino-acid requirements relative to those in normal, non-stressed individuals
