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An enzyme called Carnitine Palmitoyltransferase I (CPT1), located on the outer mitochondrial membrane, attaches a molecule of L-carnitine to the long-chain fatty acid, creating an acylcarnitine complex

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In this respect, an interesting study conducted on immortalized human microglia cells (CVCL_5G94) highlighted how ATRAs can increase the heat shock protein 90 (Hsp90) expression on the surface of these cells, causing an increase in the amount of endocytosed and consequently eliminated tau protein (25)