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Protective Effects of Picrorhiza Kurroa on Cyclophosphamide-Induced Immunosuppression in Mice

Statistics and reproducibility All statistical analyses were performed using SPSS 16.0

rather, it inhibits COX-2 synthesis indirectly by obstructing transcriptional activation via the NF-B and AP-1 pathways

Next we determined whether hypoxia-inducible factor 1 (HIF1), adenosine monophosphate-activated protein kinase (AMPK) or mammalian target of rapamycin complex 1 (mTORC1) promoted the observed phenotype as these proteins are established regulators of energy metabolism 20,21,22
