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22 October 2024 The World Anti-Doping Agency (WADA) has published its 2025 Prohibited List

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Side effects appear to be infrequent and mild in most reported cases, and may include: Temporary injection site reactions (with subcutaneous administration) Mild headache in some individuals Vivid dreams often considered a sign of enhanced REM sleep activity Occasional mild gastrointestinal discomfort DSIP does not appear to suppress respiratory function or cause the cognitive impairment sometimes associated with sedative-hypnotic drugs

In fibrotic tissues, the level of PAI-1 is elevated, contributing to excessive accumulation of collagen and other ECM proteins in the wound area, preventing tissue proteolytic activities and thus preserving scarring [50]