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doi: 10.1002/ptr.3476 35
Signaling: Steroid hormones (testosterone, estrogen, cortisol) and eicosanoids regulate processes like inflammation, blood clotting, and immune responses

Nature 424, 277283.10.1038/nature01789 73 NichollsD

As ammonia levels rise, symptoms can progress to hyperventilation resulting in respiratory alkalosis, hypotonia, ataxia, disorientation, seizures and, if untreated, coma and death 15