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However, the presence of -glutamyl transpeptidase (GT) may present a challenge, because it can not only decompose soluble GSH but also GSSP

[PMC free article: PMC1894911] [PubMed: 15900287] (In human volunteer studies, kava showed moderate inhibition of CYP 2E1 activity [40%] but no effect on CYP 1A2, 2D6 or 3A4, despite evidence in vitro that kava inhibits these isoenzymes

Variable selection based on second-order Akaike information criterion are performed using R ( Results Study Demographics For this study, 24 patients with a diagnosis of MS (18 relapsing remitting and six primary progressive) were enrolled for this preliminary assessment, with 12 patients randomized to the NAC arm (10F/2M

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