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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Unal H, Karnik SS
DOI:10.1073/pnas.94.25.13997 50

In some embodiments, preparation of certain cations of the invention may occur via oxidation of quinoline (using e.g., mCPBA) followed by nitration and chlorination, respectively and further followed by amination and alkylation, respectively, as exemplified with the preparation of cation 2k (Scheme 4)

This can proceed as the advantageous application of the principle of vascular cytoprotection [129,130,131,132,133,134,135,136,137,138,139,140,141,142,168]
