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Four trials registered their protocols, and three trials (Jamilian et al., 2017
Arginine, hippuric acid, dimethylarginine, butenoylcarnitine, indoxyl sulfate, sorbitol (in serum), and p-CS (in urine) served as possible biomarkers for early diabetes kidney disease (Balint et al., 2023c)
Each of the approaches evaluated here has its own specific advantages and limitations, which are summarized in Table 1
