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KPV inhibitsNF-B activation at nanomolar concentrations through stabilization of IB- and prevention of p65RelA nuclear translocation[13]
Ashmarin, I.P., Nezavibatko, V.N., Myasoedov, N.F., Kamensky, A.A., Grivennikov, I.A., Ponomareva-Stepnaya, M.A., Andreeva, L.A., Kaplan, A.Y., Koshelev, V.B., and Ryasina, T.V., Zh
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Compared to GLP- 1 receptor mono-agonists and GLP- 1 receptor/GIP receptor co-agonists, optimized triagonists improve energy expenditure and restore body weight in DIO mice
