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doi:10.1016/s0014-5793(02)03066-1

However, the aforesaid method suffers from disadvantages such as a difficulty to perform recrystallization and high production costs due to the use of an expensive optical resolution reagent

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Considerable controversy has surrounded terms such as dysplastic nevus , and the 1992 Nation Institutes of Health Consensus Conference recommended the use of the more clinically descriptive term atypical nevus
