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Following unilateral intrastriatal or medial forebrain bundle injection of 6-hydroxydopamine (6-OHDA)a classical neurotoxin used to mimic parkinsonian neurodegenerationthey observed pronounced leakage of FITC-labeled albumin and horseradish peroxidase into the ipsilateral striatum and substantia nigra at both 10 and 34 days post-lesion

Systemic oxygenation strategies include the administration of erythropoietin to increase hematocrit levels, apparatus to effect continuous positive airway pressure, and whole-body chambers to produce an environment of 100% oxygen

Although there have been positive outcomes in lab tests, both peptides are research chemicals, with their effectiveness and patient safety in humans not fully proven

Injectable epithalon is available in 50mg vials through our preferred vendor, who we discuss in the next section