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To avoid disrupting the balance from OS to RS, antioxidant therapy must be judiciously administered to achieve and sustain redox homeostasis, a critical factor in the management of male infertility [12] (Fig

This suggests that PIEZO1 was essential for regulating PHB2 phosphorylation and mediating the mitochondrial protective effects of the nano-formulation

Moreover, several in vitro and in vivo studies supported the beneficial role of albumin in stabilizing the endothelial cell function, which may be due to albumin's antioxidant and inflammation-regulating properties to protect endothelial cells from damage by pro-inflammatory factors (60,61)

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