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Supplementing B12 can lower homocysteine, an amino acid in your bloodstream

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Retrospective studies have shown dose escalation response rates of 6696% among all patients who have lost response to doses of 5mg/kg every 8 weeks, with one study observing the response rate to IFX escalation to be 88% in patients without antibodies to infliximab [ATI] compared with 33% among those with ATIs

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Consistently, the risk of bias assessment, revealed a moderate risk for the first 6 studies scoring three points, and high risk for the 4 studies scoring five points

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