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Nevertheless, although the differences in the metabolic states of M1 and M2 are well accepted, the underlying mechanisms involved in switching between metabolic states are not well understood
Both patients and physicians made a global evaluation at week 4 to evaluate the improvement achieved at the end of therapy as significant, moderate, mild or as absent
This may increase longevity of healthy cells, but there are concerns that by increasing the longevity of bad cells the same mechanism could lead to adverse outcomes [32, 33]
L.SathanooriR.MuldoonM
