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Description
This discovery of filamentation evaded past crystallographic studies involving an engineered protein that removes a surface loop (residues 516525) 16,17,18 now revealed to be key to polymerisation, alongside the assumption that CBS is predominantly a tetrameric protein 12

Certain people should not take metformin due to the increased risk of severe side effects or complications

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Non-HLA gene polymorphisms in the pathogenesis of type 1 diabetes: phase and endotype specific effects
