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In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions

It is possible that the generation of cADPR could be part of a byproduct of the NAD + glycohydrolase activity of CD38

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AOD-9604 stimulates lipolysis and inhibits fat cell formation, CB4211 enhances insulin sensitivity and fatty acid metabolism, and Tesamorelin targets visceral fat through growth hormone-mediated pathways