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Description
Examples of chemical modifications that extend the half-life of SOD1 and improve its pharmacological profile include coupling of polyethylene glycol, lecithin, putrescine, and sugars (for a review, see Ref

PMID: 2039442

10.1200/JCO.2010.33.6297 [DOI] [PubMed] [Google Scholar] Han C

The initial purpose of the Rumack-Matthew nomogram was for acute ingestions of APAP and its use has not been validated for chronic ingestions, extended-release preparations or co-ingestions of APAP with other substances that may be hepatically cleared
