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Description
In preclinical studies, metformin activates AMPK via inhibition of mitochondrial complex I, enhancing mitochondrial biogenesis and mitophagy [148], while pioglitazone promotes fatty acid oxidation, energy production, and reduces neuroinflammation [149]
( b ) Schematic of the syngeneic mouse experiment (Vehicle, n = 6
& Margel, S
I put ice in the Shaker first, then the mix, then water
