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Thus, this suggests a potential epigenetic regulatory mechanism that might contribute to the pathogenesis of RM ( Animal models have been instrumental in elucidating the role of ferroptosis in RM
Since the production of glutathione occurs exclusively in the cytosol and mitochondria lack the enzymes of glutathione synthesis and thus all mitochondrial glutathione must be imported
1059 For complex IV and ATP synthesis, inhibitors such as resveratrol and oligomycin have shown promising antitumor activity in skin cancer, neuroblastoma, and lymphoblastic leukemia models
Cell 1990;62:599608
