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It works systemically to support regeneration throughout the body, including skin tissue that has been compromised by aging, sun exposure, or injury
e-Pub 2012

Patients who have had such reactions to previous therapy with acetylcysteine may not react during subsequent therapy with the drug, and patients who have had inhalation treatments with acetylcysteine without incident may react to subsequent therapy
Jump in 1 mg increments only after Phase 3
