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Thyroid Dysfunction Uncontrolled thyroid disorders may heighten susceptibility to side effects, especially those affecting metabolism or cardiovascular function

Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management