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Methylation is the magical process that helps regulate gene expression
The enhancement of PDHC acetylation through ACAT1 activation helps recruit PDK to the phosphorylation sites of PDH, thus inducing a decrease in PDHC activity, while the blockade of PDHC acetylation through SIRT3 activation may lead to its dephosphorylation and activation (31)
[DOI] [PubMed] [Google Scholar] 50.Yu M., Wang H., Xu Y., Yu D., Li D., Liu X., Du W
However, compared with human and model organisms, epigenetic studies in livestock is less developed
