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The downstream mechanisms of DR involve mitochondrial functions, various stress responses, autophagy, proteostasis, and metabolism 11,12,13,15,16,18,19

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[DOI] [PubMed] [Google Scholar] 34.Perlemuter G, Sabile A, Letteron P, Vona G, Topilco A, Chretien Y, et al

Additionally, CEBPB directly activates the PTCSC3 promoter, and its disruption by rs944289 attenuates PTCSC3 expression, promoting tumorigenesis
