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In the next reaction, 2-methyl-3-hydroxybutyryl-CoA is metabolized to 2-methylacetoacetyl-CoA by hydroxysteroid 17-beta dehydrogenase 10 which is encoded by the HSD17B10 gene
In fact, an increase in the permeability of the intestine due to changes in the functioning and/or in the expression levels of the TJ proteins cause leaky gut syndrome or LGS
doi: 10.1016/j.plefa.2020.102236 79 NafarF.MearowK
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