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1 , 2 , 12 14 Recent pharmacokinetics modeling 15 indicates that with oral administration, even very large and frequent doses of vitamin C will increase plasma concentrations only modestly, from 70 mol/L to a maximum of 220 mol/L, whereas intravenous administration raises plasma concentrations as high as 14 000 mol/L

The phosphate bonds in ATP form are produced in a substantial amount by glycolysis and oxidative phosphorylation

2 Such future research could be enhanced with genomics approaches

Glial fibrillary acidic protein (GFAP) was increased in the cohort with brain fog compared to recovered individuals while only transforming growth factor- (TGF) was selectively increased in the cohort with brain fog compared to the cohort with long COVID without brain fog (Fig