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In addition, GTC did not alter anticoagulant activity but mainly altered antiplatelet activity to exert antithrombotic effects in human platelet aggregation assays induced by ADP, collagen, epinephrine, and the calcium ion polymer A23187 in vitro (141)

Oxidative stress promotes myocardial fibrosis by upregulating KCa3.1 channel expression in AGT-REN double transgenic hypertensive mice

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Figure 2 2.2 Dynamic polarization and functional switch of macrophages Macrophages directly recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) via surface pattern recognition receptors (PRRs) and opsonin receptors, internalizing them via receptor-mediated endocytosis