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It was found that cells harboring IDH1-R132 and IDH2-R172 mutations in patients with acute myeloid leukemia gained the ability to convert -KG to D-2HG [22]
10.1038/bjp.2008.118 67 KidoK.AtoS.YokokawaT.MakanaeY.SatoK.FujitaS
( 2 + (Kagan et al., 2017)
