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However, it has been classified as GRAS (Generally Recognized As Safe) as a food additive, and is commonly used in regenerative medicine under professional supervision

3T3-L1 pre-adipocytes cells were cultured with standard culture media (DMEM, 4.5 g/L glucose, L-glutamine, sodium pyruvate, 10% FBS, 1% antibiotic-antimycotic solution) and grown for 48 h before initiating differentiation using the manufacturer's suggested protocol and modified from previous published work

These systems-level insights may identify new research applications and combination strategies that enhance the compound's utility as an experimental tool

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