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Specifically, this effect is mediated through an increase in butyrate-producing bacteria (such as FP , Roseburia , Butyricicoccus porcorum , and Gemmiger formicilis ) and a decrease in conditionally pathogenic bacteria (including Akkermansia and Parasutterella excrementihominis )

qRTPCR reaction was performed using LightCycler 2.0 system (Roche, Germany)

Nature , 402(6762), 656660

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